Publications
Duarte-Neves J, Gonçalves N, Cunha-Santos J, Simões AT, den Dunnen WF, Hirai H, Kügler S, Cavadas C, Pereira de Almeida L. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease. Hum Mol Genet. 2015 Jul 27. pii: ddv271. PUBMED
Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster M, Aveleira CA, Ferreira M, Álvaro AR, Cavadas C. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. Eur Neuropsychopharmacol. 2015 Jul 2. pii: S0924-977X(15)00183-2. doi: 10.1016/j.euroneuro.2015.06.013. PUBMED
Aveleira CA, Botelho M, Cavadas C. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? Autophagy. 2015 Aug 3;11(8):1431-3. doi: 10.1080/15548627.2015.1062202 PUBMED
Santos-Carvalho A, Ambrósio AF, Cavadas C. Neuropeptide Y system in the retina: From localization to function. Prog Retin Eye Res. 2015 Mar 19. pii: S1350-9462(15)00016-6. doi: 10.1016/j.preteyeres.2015.03.00 PUBMED
Aveleira CA, Botelho M, Carmo-Silva S, Pascoal JF, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, Sousa-Ferreira L, Álvaro AR, Santana M, Kügler S, Pereira de Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1642-51. doi: 10.1073/pnas.1416609112. PUBMED
Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro AR, Pereira de Almeida L, Cavadas C. Flouxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro. PLos One. 2014 Mar 5; 9(3):e88917 PUBMED
Sousa-Ferreira L, de Almeida LP, Cavadas C. Role of hypothalamic neurogenesis in feeding regulation. Trends Endocrinol Metab. 2014 Feb; 25(2):80-8 PUBMED
Santos-Carvalho A, Alvaro AR, Martins J, Ambrósio AF, Cavadas C. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection. Prog Neurobiol. 2014 Jan; 112:70-9 PUBMED
Vindeirinho J, Costa GN, Correia MB, Cavadas C, Santos PF. Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. PLos One. 2013 Jun 28; 8(6):e67499 PUBMED
Santos-Carvalho A, Elvas F, Alvaro AR, Ambrósio AF, Cavadas C. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell Death Dis. 2013 May 16; 4e636 PUBMED
Santos-Carvalho A, Aveleira CA, Elvas F, Ambrósio AF, Cavadas C. Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture. Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):429-43. PUBMED
Santana MM, Chung KF, Vukicevic V, Rosmaninho-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med. 2012 Nov;1(11):783-91 PUBMED
Rosmaninho-Salgado J, Cortez V, Estrada M, Santana MM, Gonçalves A, Marques AP, Cavadas C. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes. Neuropeptides. 2012 Dec;46(6):359-66. PUBMED
Rosmaninho-Salgado J, Marques AP, Estrada M, Santana M, Cortez V, Grouzmann E, Cavadas C. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression. Peptides. 2012 Sep;37(1):49-54. PUBMED
Cortez V, Santana M, Marques AP, Mota A, Rosmaninho-Salgado J, Cavadas C. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors. Neurochem Int. 2012 Mar;60(4):387-93. PUBMED
L. Sousa-Ferreira, M. Garrido, I. Nascimento-Ferreira, C. Nobrega, A. Santos-Carvalho, A.R. Álvaro, J. Rosmaninho-Salgado, M. Kaster, S. Kügler, L. Pereira de Almeida, C. Cavadas. Moderate long-term modulation of Neuropeptide Y in the Arcuate Nucleus induces energy balance alterations in adult rats. PLoS One 2011 6(7):e22333, 2011 PUBMED
L. Sousa-Ferreira, A.R. Álvaro, C. Aveleira, M. Santana, I. Brandão, S. Kügler, L. Pereira de Almeida, C. Cavadas. Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons expressing appetite-related neuropeptides. PLoS One 6(5):e19745, 2011. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C.- Neuropeptide Y inhibits [Ca(2+)]i changes in rat retinal neurons through NPY Y(1), Y(4) and Y(5) receptors. J Neurochem. 2009, 109:1508-1515. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Mendes AF, Ferreira L, Grouzmann E, Mota A, Duarte EP, Cavadas C. - Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1beta: role of neuropeptide Y and nitric oxide. J Neurochem. 2009, 109: 911-22. PUBMED
Ruohonen ST, Savontaus E, Rinne P, Rosmaninho-Salgado J, Cavadas C, Ruskoaho H, Koulu M, Pesonen U. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons. Neuroendocrinology. 2009, 89:351-60. PUBMED
Alvaro AR, Martins J, Araújo IM, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C. - Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide. J Neurochem. 2008. 105, 2501-2510. PUBMED
Alvaro AR, Martins J, Costa AC, Fernandes E, Carvalho F, Ambrósio AF, Cavadas C. - Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy. Neuroscience. 2008 , 152:97-105. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Duarte EP, Cavadas C. Intracellular Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells. J Neurochem. 2007;103(3):896-903. PUBMED
Rosmaninho-Salgado J, Alvaro AR, Grouzmann E, Duarte EP, Cavadas C. Neuropeptide Y regulates catecholamine release evoked by interleukin-1beta in mouse chromaffin cells. Peptides. 2007;28(2):310-4. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Santiago AR, Martins J, Aveleira C, Santos PF, Pereira T, Gouveia D, Carvalho AL, Grouzmann E, Ambrósio AF, Cavadas C. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochem Int. 2007;50(5):757-63. PUBMED
Cavadas C, Céfai D, Rosmaninho-Salgado J, Vieira-Coelho MA, Moura E, Busso N, Pedrazzini T, Grand D, Rotman S, Waeber B, Aubert JF, Grouzmann E. Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion. Proc Natl Acad Sci U S A. 2006; 103(27):104 97-502. PUBMED
Silva AP, Xapelli S, Grouzmann E, Cavadas C. The putative neuroprotective role of neuropeptide Y in the central nervous system. Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):331-47. Review. PUBMED
http://www.ncbi.nlm.nih.gov/pubmed/?term=Neuropeptide+Y+mitigates+neuropathology+and+motor+deficits+in+mouse+models+of+Machado-Joseph+disease.
Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster M, Aveleira CA, Ferreira M, Álvaro AR, Cavadas C. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. Eur Neuropsychopharmacol. 2015 Jul 2. pii: S0924-977X(15)00183-2. doi: 10.1016/j.euroneuro.2015.06.013. PUBMED
Aveleira CA, Botelho M, Cavadas C. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? Autophagy. 2015 Aug 3;11(8):1431-3. doi: 10.1080/15548627.2015.1062202 PUBMED
Santos-Carvalho A, Ambrósio AF, Cavadas C. Neuropeptide Y system in the retina: From localization to function. Prog Retin Eye Res. 2015 Mar 19. pii: S1350-9462(15)00016-6. doi: 10.1016/j.preteyeres.2015.03.00 PUBMED
Aveleira CA, Botelho M, Carmo-Silva S, Pascoal JF, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, Sousa-Ferreira L, Álvaro AR, Santana M, Kügler S, Pereira de Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1642-51. doi: 10.1073/pnas.1416609112. PUBMED
Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro AR, Pereira de Almeida L, Cavadas C. Flouxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro. PLos One. 2014 Mar 5; 9(3):e88917 PUBMED
Sousa-Ferreira L, de Almeida LP, Cavadas C. Role of hypothalamic neurogenesis in feeding regulation. Trends Endocrinol Metab. 2014 Feb; 25(2):80-8 PUBMED
Santos-Carvalho A, Alvaro AR, Martins J, Ambrósio AF, Cavadas C. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection. Prog Neurobiol. 2014 Jan; 112:70-9 PUBMED
Vindeirinho J, Costa GN, Correia MB, Cavadas C, Santos PF. Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. PLos One. 2013 Jun 28; 8(6):e67499 PUBMED
Santos-Carvalho A, Elvas F, Alvaro AR, Ambrósio AF, Cavadas C. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell Death Dis. 2013 May 16; 4e636 PUBMED
Santos-Carvalho A, Aveleira CA, Elvas F, Ambrósio AF, Cavadas C. Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture. Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):429-43. PUBMED
Santana MM, Chung KF, Vukicevic V, Rosmaninho-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med. 2012 Nov;1(11):783-91 PUBMED
Rosmaninho-Salgado J, Cortez V, Estrada M, Santana MM, Gonçalves A, Marques AP, Cavadas C. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes. Neuropeptides. 2012 Dec;46(6):359-66. PUBMED
Rosmaninho-Salgado J, Marques AP, Estrada M, Santana M, Cortez V, Grouzmann E, Cavadas C. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression. Peptides. 2012 Sep;37(1):49-54. PUBMED
Cortez V, Santana M, Marques AP, Mota A, Rosmaninho-Salgado J, Cavadas C. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors. Neurochem Int. 2012 Mar;60(4):387-93. PUBMED
L. Sousa-Ferreira, M. Garrido, I. Nascimento-Ferreira, C. Nobrega, A. Santos-Carvalho, A.R. Álvaro, J. Rosmaninho-Salgado, M. Kaster, S. Kügler, L. Pereira de Almeida, C. Cavadas. Moderate long-term modulation of Neuropeptide Y in the Arcuate Nucleus induces energy balance alterations in adult rats. PLoS One 2011 6(7):e22333, 2011 PUBMED
L. Sousa-Ferreira, A.R. Álvaro, C. Aveleira, M. Santana, I. Brandão, S. Kügler, L. Pereira de Almeida, C. Cavadas. Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons expressing appetite-related neuropeptides. PLoS One 6(5):e19745, 2011. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C.- Neuropeptide Y inhibits [Ca(2+)]i changes in rat retinal neurons through NPY Y(1), Y(4) and Y(5) receptors. J Neurochem. 2009, 109:1508-1515. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Mendes AF, Ferreira L, Grouzmann E, Mota A, Duarte EP, Cavadas C. - Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1beta: role of neuropeptide Y and nitric oxide. J Neurochem. 2009, 109: 911-22. PUBMED
Ruohonen ST, Savontaus E, Rinne P, Rosmaninho-Salgado J, Cavadas C, Ruskoaho H, Koulu M, Pesonen U. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons. Neuroendocrinology. 2009, 89:351-60. PUBMED
Alvaro AR, Martins J, Araújo IM, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C. - Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide. J Neurochem. 2008. 105, 2501-2510. PUBMED
Alvaro AR, Martins J, Costa AC, Fernandes E, Carvalho F, Ambrósio AF, Cavadas C. - Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy. Neuroscience. 2008 , 152:97-105. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Duarte EP, Cavadas C. Intracellular Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells. J Neurochem. 2007;103(3):896-903. PUBMED
Rosmaninho-Salgado J, Alvaro AR, Grouzmann E, Duarte EP, Cavadas C. Neuropeptide Y regulates catecholamine release evoked by interleukin-1beta in mouse chromaffin cells. Peptides. 2007;28(2):310-4. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Santiago AR, Martins J, Aveleira C, Santos PF, Pereira T, Gouveia D, Carvalho AL, Grouzmann E, Ambrósio AF, Cavadas C. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochem Int. 2007;50(5):757-63. PUBMED
Cavadas C, Céfai D, Rosmaninho-Salgado J, Vieira-Coelho MA, Moura E, Busso N, Pedrazzini T, Grand D, Rotman S, Waeber B, Aubert JF, Grouzmann E. Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion. Proc Natl Acad Sci U S A. 2006; 103(27):104 97-502. PUBMED
Silva AP, Xapelli S, Grouzmann E, Cavadas C. The putative neuroprotective role of neuropeptide Y in the central nervous system. Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):331-47. Review. PUBMED
Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster M, Aveleira CA, Ferreira M, Álvaro AR, Cavadas C. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. Eur Neuropsychopharmacol. 2015 Jul 2. pii: S0924-977X(15)00183-2. doi: 10.1016/j.euroneuro.2015.06.013. PUBMED
Aveleira CA, Botelho M, Cavadas C. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? Autophagy. 2015 Aug 3;11(8):1431-3. doi: 10.1080/15548627.2015.1062202 PUBMED
Santos-Carvalho A, Ambrósio AF, Cavadas C. Neuropeptide Y system in the retina: From localization to function. Prog Retin Eye Res. 2015 Mar 19. pii: S1350-9462(15)00016-6. doi: 10.1016/j.preteyeres.2015.03.00 PUBMED
Aveleira CA, Botelho M, Carmo-Silva S, Pascoal JF, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, Sousa-Ferreira L, Álvaro AR, Santana M, Kügler S, Pereira de Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1642-51. doi: 10.1073/pnas.1416609112. PUBMED
Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro AR, Pereira de Almeida L, Cavadas C. Flouxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro. PLos One. 2014 Mar 5; 9(3):e88917 PUBMED
Sousa-Ferreira L, de Almeida LP, Cavadas C. Role of hypothalamic neurogenesis in feeding regulation. Trends Endocrinol Metab. 2014 Feb; 25(2):80-8 PUBMED
Santos-Carvalho A, Alvaro AR, Martins J, Ambrósio AF, Cavadas C. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection. Prog Neurobiol. 2014 Jan; 112:70-9 PUBMED
Vindeirinho J, Costa GN, Correia MB, Cavadas C, Santos PF. Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. PLos One. 2013 Jun 28; 8(6):e67499 PUBMED
Santos-Carvalho A, Elvas F, Alvaro AR, Ambrósio AF, Cavadas C. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell Death Dis. 2013 May 16; 4e636 PUBMED
Santos-Carvalho A, Aveleira CA, Elvas F, Ambrósio AF, Cavadas C. Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture. Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):429-43. PUBMED
Santana MM, Chung KF, Vukicevic V, Rosmaninho-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med. 2012 Nov;1(11):783-91 PUBMED
Rosmaninho-Salgado J, Cortez V, Estrada M, Santana MM, Gonçalves A, Marques AP, Cavadas C. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes. Neuropeptides. 2012 Dec;46(6):359-66. PUBMED
Rosmaninho-Salgado J, Marques AP, Estrada M, Santana M, Cortez V, Grouzmann E, Cavadas C. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression. Peptides. 2012 Sep;37(1):49-54. PUBMED
Cortez V, Santana M, Marques AP, Mota A, Rosmaninho-Salgado J, Cavadas C. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors. Neurochem Int. 2012 Mar;60(4):387-93. PUBMED
L. Sousa-Ferreira, M. Garrido, I. Nascimento-Ferreira, C. Nobrega, A. Santos-Carvalho, A.R. Álvaro, J. Rosmaninho-Salgado, M. Kaster, S. Kügler, L. Pereira de Almeida, C. Cavadas. Moderate long-term modulation of Neuropeptide Y in the Arcuate Nucleus induces energy balance alterations in adult rats. PLoS One 2011 6(7):e22333, 2011 PUBMED
L. Sousa-Ferreira, A.R. Álvaro, C. Aveleira, M. Santana, I. Brandão, S. Kügler, L. Pereira de Almeida, C. Cavadas. Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons expressing appetite-related neuropeptides. PLoS One 6(5):e19745, 2011. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C.- Neuropeptide Y inhibits [Ca(2+)]i changes in rat retinal neurons through NPY Y(1), Y(4) and Y(5) receptors. J Neurochem. 2009, 109:1508-1515. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Mendes AF, Ferreira L, Grouzmann E, Mota A, Duarte EP, Cavadas C. - Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1beta: role of neuropeptide Y and nitric oxide. J Neurochem. 2009, 109: 911-22. PUBMED
Ruohonen ST, Savontaus E, Rinne P, Rosmaninho-Salgado J, Cavadas C, Ruskoaho H, Koulu M, Pesonen U. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons. Neuroendocrinology. 2009, 89:351-60. PUBMED
Alvaro AR, Martins J, Araújo IM, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C. - Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide. J Neurochem. 2008. 105, 2501-2510. PUBMED
Alvaro AR, Martins J, Costa AC, Fernandes E, Carvalho F, Ambrósio AF, Cavadas C. - Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy. Neuroscience. 2008 , 152:97-105. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Duarte EP, Cavadas C. Intracellular Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells. J Neurochem. 2007;103(3):896-903. PUBMED
Rosmaninho-Salgado J, Alvaro AR, Grouzmann E, Duarte EP, Cavadas C. Neuropeptide Y regulates catecholamine release evoked by interleukin-1beta in mouse chromaffin cells. Peptides. 2007;28(2):310-4. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Santiago AR, Martins J, Aveleira C, Santos PF, Pereira T, Gouveia D, Carvalho AL, Grouzmann E, Ambrósio AF, Cavadas C. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochem Int. 2007;50(5):757-63. PUBMED
Cavadas C, Céfai D, Rosmaninho-Salgado J, Vieira-Coelho MA, Moura E, Busso N, Pedrazzini T, Grand D, Rotman S, Waeber B, Aubert JF, Grouzmann E. Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion. Proc Natl Acad Sci U S A. 2006; 103(27):104 97-502. PUBMED
Silva AP, Xapelli S, Grouzmann E, Cavadas C. The putative neuroprotective role of neuropeptide Y in the central nervous system. Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):331-47. Review. PUBMED
http://www.ncbi.nlm.nih.gov/pubmed/?term=Neuropeptide+Y+mitigates+neuropathology+and+motor+deficits+in+mouse+models+of+Machado-Joseph+disease.
Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster M, Aveleira CA, Ferreira M, Álvaro AR, Cavadas C. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. Eur Neuropsychopharmacol. 2015 Jul 2. pii: S0924-977X(15)00183-2. doi: 10.1016/j.euroneuro.2015.06.013. PUBMED
Aveleira CA, Botelho M, Cavadas C. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? Autophagy. 2015 Aug 3;11(8):1431-3. doi: 10.1080/15548627.2015.1062202 PUBMED
Santos-Carvalho A, Ambrósio AF, Cavadas C. Neuropeptide Y system in the retina: From localization to function. Prog Retin Eye Res. 2015 Mar 19. pii: S1350-9462(15)00016-6. doi: 10.1016/j.preteyeres.2015.03.00 PUBMED
Aveleira CA, Botelho M, Carmo-Silva S, Pascoal JF, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, Sousa-Ferreira L, Álvaro AR, Santana M, Kügler S, Pereira de Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1642-51. doi: 10.1073/pnas.1416609112. PUBMED
Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro AR, Pereira de Almeida L, Cavadas C. Flouxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro. PLos One. 2014 Mar 5; 9(3):e88917 PUBMED
Sousa-Ferreira L, de Almeida LP, Cavadas C. Role of hypothalamic neurogenesis in feeding regulation. Trends Endocrinol Metab. 2014 Feb; 25(2):80-8 PUBMED
Santos-Carvalho A, Alvaro AR, Martins J, Ambrósio AF, Cavadas C. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection. Prog Neurobiol. 2014 Jan; 112:70-9 PUBMED
Vindeirinho J, Costa GN, Correia MB, Cavadas C, Santos PF. Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. PLos One. 2013 Jun 28; 8(6):e67499 PUBMED
Santos-Carvalho A, Elvas F, Alvaro AR, Ambrósio AF, Cavadas C. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell Death Dis. 2013 May 16; 4e636 PUBMED
Santos-Carvalho A, Aveleira CA, Elvas F, Ambrósio AF, Cavadas C. Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture. Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):429-43. PUBMED
Santana MM, Chung KF, Vukicevic V, Rosmaninho-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med. 2012 Nov;1(11):783-91 PUBMED
Rosmaninho-Salgado J, Cortez V, Estrada M, Santana MM, Gonçalves A, Marques AP, Cavadas C. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes. Neuropeptides. 2012 Dec;46(6):359-66. PUBMED
Rosmaninho-Salgado J, Marques AP, Estrada M, Santana M, Cortez V, Grouzmann E, Cavadas C. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression. Peptides. 2012 Sep;37(1):49-54. PUBMED
Cortez V, Santana M, Marques AP, Mota A, Rosmaninho-Salgado J, Cavadas C. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors. Neurochem Int. 2012 Mar;60(4):387-93. PUBMED
L. Sousa-Ferreira, M. Garrido, I. Nascimento-Ferreira, C. Nobrega, A. Santos-Carvalho, A.R. Álvaro, J. Rosmaninho-Salgado, M. Kaster, S. Kügler, L. Pereira de Almeida, C. Cavadas. Moderate long-term modulation of Neuropeptide Y in the Arcuate Nucleus induces energy balance alterations in adult rats. PLoS One 2011 6(7):e22333, 2011 PUBMED
L. Sousa-Ferreira, A.R. Álvaro, C. Aveleira, M. Santana, I. Brandão, S. Kügler, L. Pereira de Almeida, C. Cavadas. Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons expressing appetite-related neuropeptides. PLoS One 6(5):e19745, 2011. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C.- Neuropeptide Y inhibits [Ca(2+)]i changes in rat retinal neurons through NPY Y(1), Y(4) and Y(5) receptors. J Neurochem. 2009, 109:1508-1515. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Mendes AF, Ferreira L, Grouzmann E, Mota A, Duarte EP, Cavadas C. - Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1beta: role of neuropeptide Y and nitric oxide. J Neurochem. 2009, 109: 911-22. PUBMED
Ruohonen ST, Savontaus E, Rinne P, Rosmaninho-Salgado J, Cavadas C, Ruskoaho H, Koulu M, Pesonen U. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons. Neuroendocrinology. 2009, 89:351-60. PUBMED
Alvaro AR, Martins J, Araújo IM, Rosmaninho-Salgado J, Ambrósio AF, Cavadas C. - Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide. J Neurochem. 2008. 105, 2501-2510. PUBMED
Alvaro AR, Martins J, Costa AC, Fernandes E, Carvalho F, Ambrósio AF, Cavadas C. - Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy. Neuroscience. 2008 , 152:97-105. PUBMED
Rosmaninho-Salgado J, Araújo IM, Alvaro AR, Duarte EP, Cavadas C. Intracellular Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells. J Neurochem. 2007;103(3):896-903. PUBMED
Rosmaninho-Salgado J, Alvaro AR, Grouzmann E, Duarte EP, Cavadas C. Neuropeptide Y regulates catecholamine release evoked by interleukin-1beta in mouse chromaffin cells. Peptides. 2007;28(2):310-4. PUBMED
Alvaro AR, Rosmaninho-Salgado J, Santiago AR, Martins J, Aveleira C, Santos PF, Pereira T, Gouveia D, Carvalho AL, Grouzmann E, Ambrósio AF, Cavadas C. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochem Int. 2007;50(5):757-63. PUBMED
Cavadas C, Céfai D, Rosmaninho-Salgado J, Vieira-Coelho MA, Moura E, Busso N, Pedrazzini T, Grand D, Rotman S, Waeber B, Aubert JF, Grouzmann E. Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion. Proc Natl Acad Sci U S A. 2006; 103(27):104 97-502. PUBMED
Silva AP, Xapelli S, Grouzmann E, Cavadas C. The putative neuroprotective role of neuropeptide Y in the central nervous system. Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):331-47. Review. PUBMED